Mild encephalitis/encephalopathy with reversible splenial lesion is a clinical and radiological diagnosis and is defined as reversible diffusion restriction in the corpus callosum splenium. It is generally reported to be related with viral infections. We present 2 adult patients with reversible diffusion restriction in the corpus splenium and mild encephalitis. Mild encephalitis/encephalopathy with reversible splenial lesion has a good prognosis, but the differential diagnosis should be made from ischemia, posterior reversible encephalopathy syndrome, lymphoma, diffuse axonal damage, and extrapontine myelinolysis.
Cite this article as: Kaba E, Beyazal M, Kaya M, Çeliker FB. Mild encephalitis/encephalopathy with reversible splenial lesion: Two case reports. Current Research in MRI, 2023;2(2):38-40.