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Objective: This study aimed to evaluate the effectiveness of multiparametric prostate magnetic resonance imaging findings by scoring with the current guideline and correlating these scores with histopathology results in patients who underwent 3 T multiparametric prostate magnetic resonance imaging with the suspicion of prostate cancer and then underwent biopsy and/or radical prostatectomy.
Methods: Between January 2017 and January 2020, 399 patients who underwent imaging with the suspicion of prostate cancer and then biopsy due to elevated prostate specific antigen on the 3 T magnetic resonance imaging device were included in the study. Each patient’s multiparametric prostate magnetic resonance imaging findings were scored independently by 2 readers using Prostate Imaging Reporting and Data System v2.1. We used appropriate statistical methods to examine the correlation between Prostate Imaging Reporting and Data System v2.1 scores and Gleason scores for 399 patients.
Results: The study included 399 patients ranging in age from 24 to 89 years; mean prostate specific antigen level was 17.2 ng/mL; mean prostate gland volume was 77.2 mL; and mean prostate specific antigen density was 0.35. Spearman correlation analysis revealed a positive correlation between the increase in Prostate Imaging Reporting and Data System v2.1 scores and the pathology Gleason scores.
Conclusion: In Prostate Imaging Reporting and Data System 1 or 2 lesions, biopsy should be avoided because the risk of clinically significant cancer is low. In Prostate Imaging Reporting and Data System 3 scores, the presence of clinically significant cancer is uncertain and biopsy is required because of suspicion of prostate cancer. Lesions classified as Prostate Imaging Reporting and Data System 4 or 5 have a high sensitivity, specificity, and negative predictive value for clinically significant cancer diagnosis. Histopathological examinations of these lesions should be performed.
Cite this article as: Tonkaz G, Şenbil DC. Histopathological correlation of current prostate imaging reporting and data system scores with 3
tesla multiparametric prostate magnetic resonance imaging in detecting prostate cancer. Current Research in MRI. 2022; 1(1): 10-14.